Ezrin Tunes the Magnitude of Humoral Immunity

Ezrin tunes the magnitude of humoral immunity.

Ezrin is a member of the ezrin-radixin-moesin family of membrane-actin cytoskeleton cross-linkers that participate in a variety of cellular processes. In B cells, phosphorylation of ezrin at different sites regulates multiple processes, such as lipid raft coalescence, BCR diffusion, microclustering, and endosomal JNK activation. In this study, we generated mice with conditional deletion of ezri...

Humoral immunity in cardiomyopathy.

Sera from patients with heart disease were examined by single sandwich indirect immunofluorescence for the presence of antibodies to human heart muscle. Endocardial biopsy specimens were also examined by direct immunofluorescence for deposition of antibodies in vivo. No consistent or specific abnormality was found in the biopsy specimens or sera of patients with congestive cardiomyopathy. The p...

Cellular and Humoral Immunity

The Abstract was presented at the Fourth Herpes Virus Meeting, Cold Spring Harbor, N. Y. Dr. Pollard's present address is Division of Infectious Diseases, University of Texas Medical Branch, Galveston, Texas. Received for publicatiotn 2 October 1979 anid inl revised forimi 14 December 1979. recovery of phytohemagglutinin transformation often preceded recovery of the responses to viral antigens....

Persisting Humoral Antiviral Immunity

Humoral Immunity and Cell-Mediated Immunity